Involvement of the cutaneous microbiota in acne

September 13, 2024

Acne vulgaris mainly affects teenagers, but it can also affect adults as either a persistent or a late-onset disorder. In addition to having an aesthetic impact, this skin disorder also affects the emotional wellbeing of affected individuals. The development of acne lesions results from various factors, with recent studies showing that dysregulation of the skin microbiota plays a major role.

Indeed, many resident microorganisms help our skin fight against external aggressors. The balance of this population of bacteria and fungi is very delicate and it can easily be modified by hormonal changes, pollution, sun exposure, or aggressive products.

Skin dysbiosis can then lead to local inflammatory reactions and the development of acne lesions: microcomedones and comedones during subclinical stages, and papules and pustules in more advanced inflammatory stages.

The study of the skin microbiota and the search for dermocosmetic solutions to maintain a balanced microbiota constitutes a new research approach to identify ingredients that help prevent or reduce the development of acne lesions and limit the use of local or systemic antibiotics.

Our medical writing team recently assisted a client in the drafting of two articles that reported on the role of the skin microbiota in acne, and demonstrated the beneficial effects of a plant-based dermocosmetic product on acne lesions. Both open access articles have been published in the Journal of the European Academy of Dermatology and Venereology (JEADV). Find out more here: https://onlinelibrary.wiley.com/toc/14683083/38/S7